恭喜邦菲生物客户Nature Communications（IF14.9） 杂志发表文章
来源: | 作者:bangfei | 发布时间: 2023-04-18 | 1537 次浏览 | 分享到:

杂志：Nature Communications，IF：14.9

期刊名：The N-terminus of an Ustilaginoidea virens Ser-Thr-rich glycosylphosphatidylinositol-anchored protein elicits plant immunity as a MAMP

见刊时间：2021.4

实验方法：Label-free

文件链接：http://www.nature.com/articles/s41467-021-22660-9

许多病原体通过特定器官感染宿主，例如感染水稻穗的Ustilaginoidea病毒。在这里，我们表明，来自U. virens的富含Ser-Thr的富含Ser-Thr的糖基磷脂酰肌醇锚定蛋白（SGP1）在水稻叶片中诱导免疫反应，但不诱导穗状物。SGP1广泛分布在真菌中，并作为本氏猪笼草BAK1依赖性防御反应的蛋白质，热稳定诱发剂。植物特异性识别其N末端的22个氨基酸肽（SGP1 N末端肽22，SNP22），诱导细胞死亡，氧化爆发和防御相关基因表达。暴露于SNP22可增强水稻免疫信号传导和对多种真菌和细菌病原体感染的抵抗力。有趣的是，虽然SGP1可以激活叶片中的免疫反应，但SGP1是体内水稻穗感染所必需的，这表明它有助于适应穗的病原体的毒力

Abstract


Many pathogens infect hosts through specific organs, such as Ustilaginoidea virens, which infects rice panicles. Here, we show that a microbe-associated molecular pattern (MAMP), Ser-Thr-rich Glycosyl-phosphatidyl-inositol-anchored protein (SGP1) from U. virens, induces immune responses in rice leaves but not panicles. SGP1 is widely distributed among fungi and acts as a proteinaceous, thermostable elicitor of BAK1-dependent defense responses in N. benthamiana. Plants specifically recognize a 22 amino acid peptide (SGP1 N terminus peptide 22, SNP22) in its N-terminus that induces cell death, oxidative burst, and defense-related gene expression. Exposure to SNP22 enhances rice immunity signaling and resistance to infection by multiple fungal and bacterial pathogens. Interestingly, while SGP1 can activate immune responses in leaves, SGP1 is required for U. virens infection of rice panicles in vivo, showing it contributes to the virulence of a panicle adapted pathogen.